SkinMedica HA⁵® Hydra Collagen Replenish + Restore Hydrator is an Evolution in Hydration – Introducing the next-gen HA⁵®, now with 2X more hyaluronic acid. Enhanced with Hydra Collagen for instant hydration and smoothness, plus Advanced VITISENSCE® Technology to replenish natural humectants, including HA and help restore skin’s hydration reservoir.

Provides immediate hydration lasting up to 48 hours. Enjoy visibly plump, dewy, and healthier-looking skin with fewer lines.

HA⁵® Hydra Collagen Replenish + Restore Hydrator attracts and retains water for instant hydration and visibly plump, smooth skin

In a clinical study, patients reported they looked ~ 3 years younger by week 121

Clinically proven to improve hydration and support skin health by addressing the skin barrier and water-holding capacity

HA⁵® Hydra Collagen Replenish + Restore Hydrator is our next level hydrator solution clinically proven to visibly improve hydration and support skin health, by improving the skin’s barrier and water-holding capacity.

It has 2X more HA than the previous formulation to provide optimal, immediate hydration. It’s our first and only hydrator to use our proprietary HA⁵® Hydra Collagen technology and Advanced VITISENSCE® Technology, targeting existing collagens deeper within the skin to boost hydration naturally. Provides long-term results that reduce the appearance of lines and redness.

In Clinical Studies

• 93% of patients reported this product made their skin look dewy and healthy at 2 weeks (n=30)
• 93% reported skin looked visibly plumper at week 12 (n=29)
• 97% of patients agreed this product improved their skin quality at week 12 (n=29)
• 100% of patients agreed this product made them feel confident about their skin at week 12 (n=29)

Advanced VITISENSCE® Technology

Features a blend of nutrients found in nature, targeting existing collagens within the skin to boost hydration naturally.

Avocado Oil Esters – Supports skin’s natural hydration and skin’s water-holding abilities
Vitamin F – Supports skin barrier and prevents water loss
Passion Fruit Seed Oil – Enhances skin health and supports skin’s water and nutrition flow
Vitis Flower Stem Extract and Lotus Sprout Extract – Protect against oxidative stress
Proprietary HA⁵® Hydra Collagen Complex

Hydration Collagen – vegan collagen that attracts and retains water for instant hydration and smoothness

5 Forms of HA:

Vectorized Time Release HA – A SkinMedica® proprietary ingredient for sustained release of HA
Cross-linked HA – Provides long-lasting hydration
Encapsulated HA – For immediate hydration
Noncross-linked HA – For smoothness and hydration
Nano-hyaluronic acid – Soothes skin

When to Apply:

Apply twice daily— morning and at night—after cleansing and treating your skin. Use before you moisturize and apply SPF.

Where to Apply:

Apply to face, neck and chest, or any area needing hydration.

How to Apply:

Dispense 1 to 2 pumps in your palm and smooth onto the skin. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.